Blues suffered a disappointing and heavy loss at the KCOM Stadium.BCFC
In truth, Pep Clotet's side could have no complaints about the defeat as they were unusually off the pace.
Blues at times laboured against Hull, particularly with their speed on the break. And the normally resolute and creative Blues midfield was far too easily by-passed.
Hull took the lead just seconds before half-time through Tom Eaves, before second-half goals from Kamil Grosicki and substitute Keane Lewis-Potter capped off a miserable afternoon for Blues.
However, with the game locked at 0-0 Jeremie Bela seemed to have been felled from behind by as he geared up to shoot in the box. But no penalty was forthcoming, and a foul on Lukas Jutkiewicz, which enabled Hull to seize possession and break to score the decisive second goal, enraged Blues.
There were two changes to the Blues starting line-up, with a return for Fran Villalba in place of Alvaro Gimenez and Josh McEachran coming in for David Davis.
Blues were given a scare within the opening two minutes after Hull burst forward on the break through Leonarda Da Silva.
His pass found Josh Bowler, but the Hull player's left-footed attempt was deflected behind for a corner by Geraldo Bajrami.
Hull were continuing to dominate most of the early play and won themselves a succession of corners without capitalising from them.
Blues had their first sight on goal on 14 minutes after Bela cut in from the right before trying his luck with a curling left-footed shot which passed several yards wide of the far post.
Hull have a golden opportunity to break the deadlock after a loose pass by Blues saw them lose the ball to the hosts who broke forward quickly.
Grosicki's cross found Jarrod Bowen in the centre of the box, but he scuffed his chance and missed the target.
Seconds later Blues had a really decent shout for a penalty denied after Bela appeared to be caught from behind by Da Silva - he got his trailing leg - as he was about to let fly with a shot inside the area, but referee Backhouse waved away their appeals.
With just under half an hour played, Hull 'keeper George Long was tested for the first time as he was forced to parry away Villalba's powerful strike from just outside the box.
Having weathered the early Hull pressure Blues were slowly starting to show what they were what they were capable of as an attacking unit and putting some decent passages of play together.
But at the same time Hull were looking a threat themselves particularly on the counter, and Connal Trueman was forced to save low down to his right from Bowen.
Bela was looking the liveliest player for Blues and the winger fired another shot wide of the upright.
As the half entered its final five minutes Blues were in the ascendancy and they won a trio of corners.
But with just seconds to half-time Hull won a soft corner. The ball was fired in by Grosicki and met well by Eaves who made no mistake as he glanced it past Trueman to give the hosts the lead.
Half-time: Hull City 1 Blues 0
Blues began the second-half kicking towards the 1,100 or so Blues fans behind the goal.
Blues won themselves an early corner after Villalba’s shot was deflected behind, but they failed to execute their short corner routine properly and the attack broke down.
Blues were almost caught out on the break when they allowed Hull to speed down the left side, but from 20 yards or so Bowler curled his shot wide.
Pep Clotet made his first change of the afternoon after 54 minutes when he sent on striker Alvaro Gimenez in place of Jude Bellingham.
Blues were often wasteful in possession, giving themselves headaches when Hull broke from their own errors, and Bajrami was forced into a last-ditch challenge on the edge of his own box to dispossess Bowen.
Hull doubled their advantage just before the hour mark.
Bowen sent Grosicki through into clear space and he ran on before dinking the ball over Trueman as he came to meet him in the box.
But the reaction from the Blues technical area was one of fury as Clotet and Craig Gardner both took issued with the referee via the fourth official as Jutkiewicz was hauled down, but no free-kick was given - sparking the transition of possession and finish.
Clotet looked to change things further when he made his second substitution after 64 with Jefferson Montero replacing Villalba.
Blues were huffing and puffing but were failing to carve out any decent openings and were generally resorting to shots from distance.
But when a great opportunity arose, they failed to take it.
Montero's cross found Gimenez, but from just six yards he headed wide when he really should have scored.
Six minutes later the Spaniard tried his luck with another header but once again he nodded wide, although it was a more difficult opening than his previous one.
Things went from bad for worse for Blues with just two minutes of normal time remaining as a through ball found Lewis-Potter and he finished clinically to give his side a third goal.
Hull City (4-2-3-1): Long, Lichaj, de Wijs, Burke, Eaves (Lewis-Potter, 75), Grosicki (Honeyman, 80), Bowler (Batty,53) Bowen, Elder, Irvine, Da Silva Lopes.
Subs (not used): Ingram (GK), Tafazolli, Kingsley, Pennington.
Bookings: Lichaj (51)
Goals: Eaves (45+1), Grosicki (58), Lewis-Potter (88).
Blues (4-2-3-1): Trueman, Pedersen, Colin, Jutkiewicz, Bela, Dean, McEachran (Crowley, 69), Villalba (Montero, 64), Bellingham (Gimenez, 54), Sunjic, Bajrami.
Subs (not used): Camp (GK), Maghoma, G Gardner, Davis.
Bookings: McEachran (64), Crowley (85).
Attendance: 11,334 (1,082 Blues fans).
Referee: Anthony Backhouse.