It finished all-square at Hillsborough on Wednesday evening as Blues were denied a win after The Owls struck a late equaliser.
Spanish striker Alvaro Gimenez fired Blues in front just into the second-half, but the South Yorkshire side claimed a point through Kadeem Harris's 81st minute strike.
Pep Clotet elected to make two changes to his starting XI with Alvaro Gimenez replacing Lukas Jutkiewicz and Fran Villalaba coming in for Jacques Maghoma.
In what a scrappy opening to the game, it was Wednesday who were generally looking the more threatening side.
And it was the hosts that had the first attempt on goal after nine minutes when the ball fell to Steven Fletcher, but the Owls striker was just off target with his volleyed effort.
On 12 minutes Jude Bellingham laid the ball off to Jeremie Bela. The Frenchman stepped to the side to avoid his marker and tried his luck from distance, but he failed to get a good connection on the ball and scuffed it well wide of the goal.
Whilst Blues were looking to string passes together, Wednesday seemed content to launch long balls into Fletcher.
Connal Trueman needed to be alert to punch Adam Reach's dangerous cross away from inside his own six-yard box.
Fran Villalba was the first player for Blues to have a shot on target just ahead of the half-hour mark when he tried his luck with a low effort from just outside the box, but it was comfortably saved by Cameron Dawson between the Wednesday sticks.
Blues were looking slightly shaky in defence and they were almost made to pay when Kieran Lee beat the offside trap, but Trueman made himself big and produced a sharp save to deny the Wednesday man.
There were promising signs by Blues when they actually getting into Wednesday half, but there a lack of incisiveness with a final ball which would unlock the home defence.
Wednesday were inches away from taking the lead when Moses Odubajo cut in from the right and unleashed a ferocious effort which flicked off the top of the cross bar and behind.
Half-time: Sheffield Wednesday 0 Blues 0
Blues began the second-half kicking towards the Blues fans located in the Leppings Lane End of the stadium.
And with less than three minutes played the visiting fans were celebrating as Gimenez fired Blues in front.
Bellingham broke up the play before finding Crowley. Crowley did well to find Bela on the right who slid in an exquisite low pass which Gimenez met at the near post and turned home with just one touch, showing a real poacher's instinct.
With 55 on the clock Kadeem Harris was played through on the left, but fired straight into the side netting much to the disappointment of the home support who initially thought he had scored.
Buoyed by their goal, Blues were looking to press home their advantage and were enjoying the best spell of the game so far.
Crowley should have done better after Blues burst forward on the counter, but instead of laying the ball off to Colin he tried a shot himself, which was blocked.
A minute later at the other end of the pitch Fernando Forestieri curled an effort wide of Trueman's upright.
Blues made the first substitution of the game on 66 minutes when Jutkiewicz was sent on in place of goalscorer Gimenez.
Then minutes later Clotet made his second change with Jefferson Montero joining the action and Bela brought off.
Wednesday were becoming increasingly desperate to find a way back into the game.
Harris saw his shot deflected behind by Pedersen and then Fletcher fired over the bar.
Out of nowhere Wednesday found an equaliser after 81 minutes when Harris was allowed to run on towards the Blues area and struck a low shot which went through a defender's legs and beat Trueman inside his far post.
Wednesday began to pour forward in search of a winner and Trueman did well to thwart Nuhiu before Marc Roberts was forced to head Luongo's header of his own line.
Sheffield Wednesday: Dawson, Fox, Lee (Forestieri, 56), Fletcher, Bannan, Borner (Lees, h/t), Reach (Nuhiu, 67), Luongo, Odubajo, Iorfa.
Subs (not used): Jones, Pelupessy, Murphy, Hutchinson.
Goals: Harris (81)
Bookings: Borner (12).
Blues: Trueman, Pedersen, Roberts, Colin, Crowley, Bela (Montero, 70), Clarke-Salter, Villalba, Bellingham (Davis, 82), Gimenez (Jutkiewicz, 66), Sunjic.
Subs (not used): Camp, Harding, McEachran, Bailey.
Goals: Gimenez (48).
Bookings: Roberts (77), Colin (84)
Referee: Peter Bankes: